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doi: 10.1093/brain/124.10.2014 29 CampbellD

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[58] Another study using intravenous infusion of n-acetylcysteine (2 hour infusion of 150 mg/kg, followed by 15 mg/kg/hour for 5 days) resulted in significantly reduced digital ulcers and lower mean recovery time on cold challenge test in 22 patients of systemic sclerosis